导师风采
0856材料与化工

李栋

  • 学院

    :材料与化学工程学院

  • 导师类别

    :博士、硕士生导师

  • 出生年月

    :198309

  • 职称

    :教授

  • 学历

    :研究生

  • 学位

    :博士

个人简介:

        三级教授,博士生导师,湖北省特聘专家。日本北海道大学博士,英国牛津大学玛丽•居里博士后研究员。湖北工业大学化学、化学工程与技术学科负责人。

        担任湖北省化学化工学会青年委员会委员、民建湖北省委科教专委会副主任委员,湖北工业大学欧美同学会/知联会理事等兼职,多个化学领域国际知名期刊审稿专家,国家自然科学基金、湖北省科学技术奖励等各类项目通讯评审专家等。


招生信息

        1.招生学科:化学,化学工程与技术,轻工技术与工程

        2.研究方向:有机合成化学,金属有机化学,有机功能材料

        3.招生年度:2023


科研项目

        1.过渡金属催化的选择性烯丙基碳-氢键氟化反应研究,国家自然科学基金项目,2014-2016,主持。

        2.过渡金属催化的新型氟化反应研究,高层次人才启动基金项目,2014-2018,主持。

        3.钯催化碳-氢键亲核氟化反应研究及其在含氟药物合成中的应用,药物合成与优化湖北省重点实验室开放基金重点项目,2017-2019,主持。

        4.含全顺式氟代环己烷结构的高频低介电聚合物研究,绿色轻工材料湖北省重点实验室开放基金重点项目,2020-2022,主持。

        5.喹啉类抗病毒药物先导化合物的绿色合成与结构优化,武汉市知识创新专项项目,2022-2024,主持。

        6.以19-羟基雄烯二酮为原料合成替勃龙的工艺开发,企业委托项目,2017-2018,主持。

        7.以20-(羟甲基)孕甾烯酮(BA)为原料合成黄体酮的工艺开发,企业委托项目,2018-2019,主持。

        8.酯化反应新型固体催化剂的开发,企业委托项目,2020-2022,主持。

        9.苯烯莫德中间体的绿色合成工艺,企业委托项目,2020-2022,主持。

        10. 5-氯-3-甲基-2-氨基苯甲酰甲胺工艺开发,企业委托项目,2019-2024,主持。


成果获奖

        2019年入选中国化学会“青年化学家元素周期表”溴元素代言人,2021年获湖北省化学化工青年创新奖。

        承担包括国家自然科学基金在内的研究项目10余项,发表SCI论文40余篇,授权发明专利20余项

    近5年发表论文:

        1. Wang, L.; Xie, L.; Fang, Z.; Zhang, Q.;Li, D.* “Tandem trifluoromethylthiolation and cyclization ofN-aryl-3-butenamides with AgSCF3: divergent access to CF3S-substituted 3,4-dihydroquinolin-2-ones and azaspiro[4,5]dienones”Org. Chem. Front. 2022,9, 3061–3067.

        2. Zhang, Q.; Deng, S.;Li, D.;* Shimokawa, J.;* Yorimitsu, H. “AgF-mediated electrophilic amination of alkoxyarylsilanes with azodicarboxylates”Chem. Asian J. 2022,17, e202101345.

        3. Hao, X.; Ji, H.; Zhan, H.; Zhang, Q.;*Li, D.* “Cobalt catalyst-controlled selective dioxygenation of styrenes using N-hydroxyphthalimide with molecular oxygen”Adv. Synth. Catal. 2022,364, 193–199.

        4. Yang, P.; Wang, X.; Wang, L.; He, J.; Zhang, Q.;Li, D.* “Oxidative cross-dehydrogenative coupling between iodoarenes and acylanilides for C–N bond formation under metal-free conditions”Org. Chem. Front. 2021,8, 2556–2562.

        5. Zhou, Z.; Ji, H.; Li, Q.; Zhang, Q.;*Li, D.*“Direct C–H aminocarbonylation of N-heteroarenes with isocyanides under transition metal-free conditions”Org. Biomol. Chem.2021,19, 2917–2922.

        6. Wang, X.; Yang, P.; Hu, B.; Zhang, Q.;Li, D.* “Hypervalent iodine reagent-promoted Hofmann-type rearrangement/carboxylation of primary amides” J. Org. Chem.2021, 86, 2820−2826.

        7. Zhou, Z.; Wu, Y.; Yang, P.; Deng, S.; Zhang, Q.;*Li, D.* “Silver-catalyzed cross dehydrogenative coupling between heteroarenes and cyclic ethers under mild conditions” ChemistrySelect2021,6, 2770–2773.

        8. Zhao, R.; Zhou, Z.; Liu, J.; Wang, X.; Zhang, Q.;*Li, D.* “Silver-catalyzedpara-selective amination and aminative dearomatization of phenols with azodicarboxylates in water”Org. Lett. 2020,22, 8144–8149.

        9. Zhang, Q.; Li, J.; Li, J.; Yuan, S.;Li, D.* “An unprecedented cobalt-catalyzed selective aroylation of primaryamines with aroyl peroxides”Tetrahedron Lett. 2020,61, 152399.

        10. Wang, X.; Liu, H.; Xiang, D.; Zhang, Q.;*Li, D.* “Hypervalent iodine reagent-mediated selective vinyl C–H amidation of 4-alkoxystyrenes with diarylsulfonimides for preparation of enamides” ChemistrySelect2020,5, 5970–5973.

        11. Wang, X.; Hu, B.; Yang, P.; Zhang, Q.;*Li, D.* “Synthesis of vinyl sulfones through sulfonylation of styrenes with sulfonyl chlorides under metal-free conditions”Tetrahedron 2020,76, 131082.

        12. 张谦;余彦葶;李家乐;李栋* “无过渡金属条件下喹啉C5位碳-氢键官能化反应”化学通报,2020, 83(7), 615–619.

        13. Chen, Q.; Yang, Y.; Wang, X.; Zhang, Q.;*Li, D.* “Hypervalent iodine reagent-mediated C5 C–H nucleophilic fluorination of 8-aminoqunolines”Chin. J. Org. Chem. 2020,40, 454–461.

        14. Li, J.; Li, J.; Yuan, S.; Zhang, Q.;*Li, D.* “Cobalt-catalyzed oxyalkylation of styrenes via α-C(sp3)–H bond activation of ethers without organic peroxides”Asian J. Org. Chem. 2019,8, 1842–1845.

        15. Xiang, D.; Li, H.; Zhang, L.; Zhang, Y.; Zhang, Q.;*Li, D.* “Divergent reactions between alkynes and dibenzenesulfonimide: selective synthesis of ynamides and enamides under metal-free conditions”Asian J. Org. Chem. 2019,8, 537–541.

        16. Zhao, R.; Yang, Y.; Wang, X.; Ren, P.; Zhang, Q.;*Li, D.* “An efficient nickel/silver co-catalyzed remote C–H amination of 8-aminoquinolines with azodicarboxylates at room temperature”RSC Adv. 2018,8, 37064–37068.

        17. Xiao, Z.; Li, J.; Yue, Q.; Zhang, Q.;Li, D.* “An efficient and atom-economical route to N-aryl amino alcohols from primary amines”RSC Adv. 2018,8, 34304–34308.

        18. Xiao, Z.; Shu, S.; Lin, Y.; Zhang, Q.; Ren, P.;*Li, D.* “Chelation-assisted C–N cross-coupling between picolinamides and aryl boronic acids under nickel catalysis”Asian J. Org. Chem. 2018,7, 2053–2056.

        19. Xiang, D.; Xia, L.; Zhang, Y.; Zhang, Q.;*Li, D.* “Remote oxidative C−H amidation of anilides with dibenzenesulfonimides under metal-free conditions”Synlett 2018,29, 1400–1404.

        20. Yue, Q.; Xiao, Z.; Kuang, Z.; Su, Z.; Zhang, Q.;*Li, D.* “Chelation-promoted efficient C–H/N–H cross dehydrogenative coupling between picolinamides and simple ethers under copper catalysis”Adv. Synth. Catal. 2018,360, 1193–1198.

        21. Yue, Q.; Xiao, Z.; Ran, Z.; Yuan, S.; Zhang, Q.;*Li, D.* “Copper-catalyzed α-C–H amidation of simple ethers through C(sp3)–H/N–H cross dehydrogenative coupling”Org. Chem. Front. 2018,5, 967–971.

        22. Xiao, Z.; Yue, Q.; Ran, Z.; Zhang, Q.;*Li, D.* “Copper-promoted N-arylation of 8-acylaminoquinoline compounds”Chin. J. Org. Chem. 2018,38, 1193–1198.

        23. Yang, Y.; Yu, Y.; Wang, Y.; Zhang, Q.;*Li, D.* “Metal-free remote oxidative benzylic C–H amination of 4-methylanilides with N-fluorobenzenesulfonimide”Tetrahedron,2018,74, 1085–1091.

        24. Zhang, C.; Yue, Q.; Xiao, Z.; Wang, X.; Zhang, Q.;Li, D.* “Synthesis ofO-aroyl-N,N-dimethyl hydroxylamines through hypervalent iodine-mediated amination of carboxylic acids withN,N-dimethylformamide”Synthesis 2017, 49, 4303–4308.

        25. Yue, Q.; Yang, T.; Yang, Y.; Zhang, C.; Zhang, Q.;Li, D.* “Divergent reactivity of (dacyloxyiodo)arenes under palladium catalysis: controlled allylic C–H acyloxylation and vinylic arylation”Asian J. Org. Chem.2017,6, 936–942.

        26. Wang, Y.; Wang, Y.; Zhang, Q.;*Li, D.* “Site-selective oxidative C–H sulfonylation of 8-acylaminoquinolines and anilides under metal-free conditions”Org. Chem. Front. 2017,4, 514–518.

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